Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473510 | 0.82 | KMT2A (0.47) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL842415 | 0.82 | KMT2A (0.47) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL28252522 | 0.78 | GPR35 (0.39) | KMT2AMEN1MAPTMAPK1KDM4E | |
| SCHEMBL28013532 | 0.77 | S100A4 (0.54) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL27879879 | 0.77 | MAOA (0.48) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL27916436 | 0.77 | KMT2A (0.43) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL28251944 | 0.77 | KDM4E (0.48) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8565807 | 0.74 | KDM4E (0.44) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL20291524 | 0.71 | CYP3A4 (0.61) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL5410460 | 0.71 | KDM1A (0.66) | KMT2AMAPTSMN1; SMN2KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794467-A | 2-amino-quinoline derivatives | 博笛生物科技有限公司 | 2018-11-13 | — | — | CN | disclosed |