Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | GPR39 | O43194 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158974 | 0.92 | NPC1 (0.64) | METNPC1RAB9APOLBCYP11B1 | |
| SCHEMBL28250224 | 0.91 | MET (0.55) | METNPC1RAB9APOLBCYP11B1 | |
| SCHEMBL30340908 | 0.81 | NPC1 (0.60) | METNPC1RAB9APOLBDYRK1A | |
| SCHEMBL2722588 | 0.80 | CBFB (0.52) | METNPC1RAB9APOLBSCN5A | |
| Ammonia Solution, Strong SCHEMBL11973863 | 0.79 | CBFB (0.51) | METNPC1RAB9APOLBSCN5A | |
| SCHEMBL30340882 | 0.79 | SCN5A (0.44) | METNPC1RAB9APOLBDYRK1A | |
| SCHEMBL1646308 | 0.77 | TGFBR1 (0.66) | MET | |
| SCHEMBL22621116 | 0.77 | SLC6A4 (0.51) | CYP11B1CYP11B2SCN5AALDH1A1SCN1A | |
| SCHEMBL3407902 | 0.76 | SLC6A4 (0.49) | NPC1RAB9ACYP11B1CYP11B2GPR39 | |
| SCHEMBL28172166 | 0.75 | PDGFRB (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108697705-A | combination product | 利物浦热带医学院 | 2018-10-23 | — | — | CN | claimed |
| CN-108697705-A | combination product | 利物浦热带医学院 | 2018-10-23 | — | — | CN | disclosed |