Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158974 | 0.88 | NPC1 (0.64) | NPC1POLBRAB9ADYRK1ANPY5R | |
| SCHEMBL30340878 | 0.86 | PIK3CB (0.42) | NPC1POLBRAB9ADYRK1AGRM5 | |
| SCHEMBL2722588 | 0.85 | CBFB (0.52) | NPC1POLBRAB9AMETSLC40A1 | |
| Ammonia Solution, Strong SCHEMBL11973863 | 0.83 | CBFB (0.51) | NPC1POLBRAB9AMETSLC40A1 | |
| SCHEMBL28253155 | 0.81 | MET (0.55) | NPC1POLBRAB9ADYRK1AMET | |
| SCHEMBL14539004 | 0.78 | NPC1 (0.66) | NPC1POLBRAB9ADYRK1ASYK | |
| SCHEMBL29757180 | 0.78 | NPC1 (1.00) | NPC1POLBRAB9ADYRK1AMCL1 | |
| SCHEMBL30743 | 0.78 | NPC1 (1.00) | NPC1POLBRAB9ADYRK1AMCL1 | |
| SCHEMBL28158378 | 0.77 | PDE4A (0.55) | DYRK1ASYKGRM5NPY5RKCNA5 | |
| SCHEMBL8103598 | 0.77 | DYRK1A (0.61) | DYRK1ASYKGRM5NPY5RSLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12383548-B2 | Antibacterial quinolines | Tecnimede—Sociedade Técnico-Medicinal, SA (PT) | 2025-08-12 | — | — | US | disclosed |
| US-20230106913-A1 | Antibacterial quinolines | TECNIMEDE - Sociedade Técnico-medicinal, SA (PT) | 2023-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12383548-B2 | Antibacterial quinolines | NQO2, RABGGTB, NQO1 | NPC1 1093/4885POLB 329/4885RAB9A 734/4885 |
| US-20230106913-A1 | Antibacterial quinolines | NQO2, RABGGTB, NQO1 | NPC1 1093/4885POLB 329/4885RAB9A 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.