Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 8/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28254764 | 0.85 | PKM (0.39) | MEN1KMT2APKMGFERGAA | |
| SCHEMBL28254690 | 0.83 | GFER (0.47) | MEN1KMT2APKMGFERGAA | |
| SCHEMBL28253899 | 0.80 | MEN1 (0.42) | MEN1KMT2APKMGFERGAA | |
| SCHEMBL28254766 | 0.75 | MEN1 (0.40) | MEN1KMT2APKMGFERGAA | |
| SCHEMBL28254732 | 0.74 | GFER (0.46) | MEN1KMT2APKMGFERGAA | |
| SCHEMBL28255841 | 0.74 | GFER (0.65) | MEN1KMT2AGFERGAAPOLB | |
| SCHEMBL25326639 | 0.73 | ALDH1A1 (0.62) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL30553383 | 0.73 | ALDH1A1 (0.62) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL28255840 | 0.73 | GFER (0.45) | MEN1KMT2APKMGFERGAA | |
| SCHEMBL20581592 | 0.70 | CYP1A2 (0.47) | MEN1KMT2AGFERGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863914-A | The hydrazide derivatives and application thereof that pyridine replaces | 广东东阳光药业有限公司 | 2018-11-23 | — | — | CN | disclosed |