Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253899 | 0.86 | MEN1 (0.42) | MEN1KMT2AGAANPSR1ALOX12 | |
| SCHEMBL28254690 | 0.81 | GFER (0.47) | MEN1KMT2AGAANPSR1ALOX12 | |
| SCHEMBL28254732 | 0.80 | GFER (0.46) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL28254764 | 0.80 | PKM (0.39) | MEN1KMT2AGAANPSR1ALOX12 | |
| SCHEMBL28255839 | 0.79 | NQO2 (0.43) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL28255840 | 0.76 | GFER (0.45) | MEN1KMT2AGAANPSR1MAPT | |
| SCHEMBL21294997 | 0.76 | CHRM5 (0.53) | MEN1KMT2ANPSR1MAPTKDM4E | |
| SCHEMBL13868460 | 0.76 | CHRM5 (0.53) | MEN1KMT2ANPSR1MAPTKDM4E | |
| SCHEMBL28254689 | 0.75 | MEN1 (0.42) | MEN1KMT2AGAANPSR1ALOX12 | |
| SCHEMBL28255841 | 0.74 | GFER (0.65) | MEN1KMT2AGAANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863948-A | The hydrazide derivatives and application thereof that pyrimidine replaces | 广东东阳光药业有限公司 | 2018-11-23 | — | — | CN | disclosed |