Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798626 | 0.84 | KMT2A (0.45) | ALDH1A1ALOX15KDM4ELMNAKMT2A | |
| SCHEMBL27684159 | 0.77 | MEN1 (0.50) | ALDH1A1KDM4ELMNAKMT2AHPGD | |
| SCHEMBL28175097 | 0.77 | FABP3 (0.49) | GPR35ALDH1A1ALOX15KDM4ELMNA | |
| SCHEMBL5285030 | 0.74 | ALDH1A1 (0.52) | GPR35ALDH1A1ALOX15KDM4ELMNA | |
| SCHEMBL28304609 | 0.74 | POLB (0.50) | GPR35ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL10586122 | 0.73 | ALDH1A1 (0.39) | ALDH1A1ALOX15LMNAKMT2AMEN1 | |
| SCHEMBL28254236 | 0.72 | CLCN2 (0.35) | ALDH1A1KDM4ELMNAKMT2AHPGD | |
| SCHEMBL3529403 | 0.71 | KMT2A (0.55) | ALDH1A1ALOX15KDM4ELMNAKMT2A | |
| SCHEMBL13602477 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AHPGDMEN1 | |
| SCHEMBL2567219 | 0.71 | ALDH1A1 (0.55) | ALDH1A1ALOX15KDM4ELMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863860-A | A kind of application of N- substituted-phenyl -3- sulphonamidobenzamide class compound and its preparation and anti-breast cancer activity | 温州医科大学 | 2018-11-23 | — | — | CN | claimed |
| CN-108863860-A | A kind of application of N- substituted-phenyl -3- sulphonamidobenzamide class compound and its preparation and anti-breast cancer activity | 温州医科大学 | 2018-11-23 | — | — | CN | disclosed |