Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 6/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 4/20 | 0.31 |
| ▸ | FLT4 | P35916 | 4/20 | 0.31 |
| ▸ | KDR | P35968 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | FABP2 | P12104 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571432 | 0.75 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL28255164 | 0.72 | GPR35 (0.37) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL7008643 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL967909 | 0.71 | CYP3A4 (0.44) | GPR27ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL103521 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTMAPK1KMT2A | |
| SCHEMBL28140899 | 0.69 | CXCR2 (0.33) | GPR27ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL7707415 | 0.67 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL10625935 | 0.66 | ALDH1A1 (0.37) | CLCN2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL106507 | 0.66 | HPGD (0.44) | CLCN2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL5798626 | 0.66 | KMT2A (0.45) | ALDH1A1LMNAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997176-A | A kind of chloro- N- substituted-phenyl -3- sulphonamidobenzamide class compound of 4- and its preparation and antitumor application thereof | 温州医科大学 | 2018-12-14 | — | — | CN | claimed |
| CN-108997176-A | A kind of chloro- N- substituted-phenyl -3- sulphonamidobenzamide class compound of 4- and its preparation and antitumor application thereof | 温州医科大学 | 2018-12-14 | — | — | CN | disclosed |
| CN-108863860-A | A kind of application of N- substituted-phenyl -3- sulphonamidobenzamide class compound and its preparation and anti-breast cancer activity | 温州医科大学 | 2018-11-23 | — | — | CN | disclosed |