Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752017 | 0.78 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1KDM4ETSHRCYP2C19 | |
| SCHEMBL1973913 | 0.78 | KDM4E (0.68) | L3MBTL1ALDH1A1KDM4ECYP2C19HIF1A | |
| SCHEMBL2750237 | 0.78 | HSPA5 (0.58) | L3MBTL1ALDH1A1HRH3HRH1HRH4 | |
| SCHEMBL3182050 | 0.77 | TSHR (0.45) | L3MBTL1ALDH1A1TSHRHRH3HRH1 | |
| Hydrochloric Acid SCHEMBL31388648 | 0.77 | KDM4E (0.71) | L3MBTL1ALDH1A1KDM4ETSHRCYP2C19 | |
| SCHEMBL29830938 | 0.76 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1TSHRHRH3HRH1 | |
| SCHEMBL41191 | 0.76 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1TSHRHRH3HRH1 | |
| SCHEMBL27808570 | 0.74 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1HRH3HRH1HRH4 | |
| SCHEMBL6378764 | 0.74 | ADRA1D (0.47) | L3MBTL1ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31659786 | 0.74 | ADRA1D (0.47) | L3MBTL1ALDH1A1KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105324379-B | Benzimidazole derivatives as bromodomain inhibitors | 吉利德科学公司 | 2018-12-04 | — | — | CN | disclosed |