Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 12/20 | 0.44 |
| ▸ | CA9 | Q16790 | 12/20 | 0.44 |
| ▸ | CA12 | O43570 | 11/20 | 0.44 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779494 | 0.79 | HDAC2 (0.43) | — | |
| SCHEMBL10707842 | 0.76 | HDAC1 (0.43) | — | |
| SCHEMBL28256379 | 0.74 | IKBKB (0.55) | SOS1CA2CA9CA12CA1 | |
| SCHEMBL1414315 | 0.72 | CA2 (0.59) | CA2CA9CA12CA1CA14 | |
| SCHEMBL28107398 | 0.72 | SOS1 (0.70) | SOS1CA2CA9CA12CA1 | |
| SCHEMBL671915 | 0.69 | CA2 (0.74) | SOS1CA2CA9CA12CA1 | |
| SCHEMBL5221358 | 0.68 | MAPT (0.61) | SOS1CA2CA9CA12CA1 | |
| SCHEMBL11577144 | 0.67 | HTR6 (0.45) | — | |
| SCHEMBL16640691 | 0.67 | IKBKB (0.57) | — | |
| SCHEMBL29032711 | 0.67 | HDAC2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108785292-A | AMINO-ARYL-BENZAMIDE COMPOUNDS AND METHODS OF USE THEREOF | 上海赫普化医药技术有限公司 | 2018-11-13 | — | — | CN | disclosed |