Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | PTGIR | P43119 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932541 | 0.83 | SIGMAR1 (0.51) | SIGMAR1PTGIRSMN1; SMN2HRH3KDM4E | |
| SCHEMBL15429645 | 0.75 | CMA1 (0.58) | SIGMAR1PTGIRSMN1; SMN2HRH3KDM4E | |
| SCHEMBL10645192 | 0.75 | TBXAS1 (0.52) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2530335 | 0.74 | CMA1 (0.56) | SIGMAR1PTGIRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28134336 | 0.73 | LMNA (0.36) | SMN1; SMN2HRH3KDM4EALDH1A1ALOX15 | |
| SCHEMBL28202883 | 0.73 | SIGMAR1 (0.44) | SIGMAR1PTGIRSMN1; SMN2HRH3KDM4E | |
| SCHEMBL28839843 | 0.72 | SIGMAR1 (0.46) | SIGMAR1PTGIRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3171551 | 0.72 | PTGIR (0.81) | SIGMAR1PTGIRSMN1; SMN2HRH3KDM4E | |
| SCHEMBL28048490 | 0.72 | PTGIR (0.75) | SIGMAR1PTGIRSMN1; SMN2HRH3KDM4E | |
| SCHEMBL1045927 | 0.72 | PTGIR (0.75) | SIGMAR1PTGIRSMN1; SMN2HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-B | Aminoheteroaryl benzamide as kinase inhibitor | 诺华股份有限公司 | 2018-11-27 | — | — | CN | disclosed |