SCHEMBL28256508

SCHEMBL28256508

Cc1ccc(S(=O)(=O)NC(C)C([O])=O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
HSD17B10 Q99714 2/20 0.57
HTT P42858 1/20 0.57
MMP2 P08253 5/20 0.56
MMP9 P14780 5/20 0.56
MMP1 P03956 4/20 0.56
MMP13 P45452 4/20 0.56
MMP3 P08254 3/20 0.56
MMP7 P09237 3/20 0.56
CA9 Q16790 4/20 0.56
CA12 O43570 2/20 0.56
CA14 Q9ULX7 1/20 0.56
CA2 P00918 5/20 0.54
ALDH1A1 P00352 2/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
CA1 P00915 4/20 0.53
MMP8 P22894 2/20 0.53
CA7 P43166 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4975578 0.86 ADAMTS4 (0.71) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL19000605 0.86 TSHR (0.61) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL698908 0.86 ADAMTS4 (0.71) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL698907 0.86 ADAMTS4 (0.71) TSHRHSD17B10HTTMMP2MMP9
Water SCHEMBL29881522 0.84 ADAMTS4 (0.69) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL5734780 0.84 TSHR (0.56) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL28502922 0.84 TSHR (0.56) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL1903552 0.84 SLC1A3 (0.56) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL5734792 0.84 TSHR (0.56) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL25269775 0.83 TSHR (0.58) TSHRHSD17B10HTTMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108956827-A A kind of method HPLC method analysis and prepare 3- (N- p-toluenesulfonyl-L- alanyl oxygroup) indoles and its enantiomter 长春百纯和成医药科技有限公司 2018-12-07 CN disclosed