SCHEMBL5734792

SCHEMBL5734792

Cc1ccc(S(=O)(=O)NC(C)C(=O)Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
HSD17B10 Q99714 2/20 0.56
HTT P42858 1/20 0.56
MMP2 P08253 5/20 0.55
MMP9 P14780 5/20 0.55
MMP1 P03956 4/20 0.55
MMP13 P45452 4/20 0.55
MMP3 P08254 3/20 0.55
MMP7 P09237 3/20 0.55
CA9 Q16790 4/20 0.54
CA12 O43570 2/20 0.54
CA14 Q9ULX7 1/20 0.54
CA2 P00918 5/20 0.53
ALDH1A1 P00352 2/20 0.53
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
CA1 P00915 4/20 0.52
MMP8 P22894 2/20 0.52
CA7 P43166 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28502922 1.00 TSHR (0.56) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL5734780 1.00 TSHR (0.56) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL3884130 0.86 MMP2 (0.57) MMP2MMP9MMP1MMP13MMP3
SCHEMBL3884127 0.86 MMP2 (0.57) MMP2MMP9MMP1MMP13MMP3
SCHEMBL698907 0.84 ADAMTS4 (0.71) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL6325782 0.84 ADAMTS4 (0.61) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL19000605 0.84 TSHR (0.61) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL698908 0.84 ADAMTS4 (0.71) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL4975578 0.84 ADAMTS4 (0.71) TSHRHSD17B10HTTMMP2MMP9
SCHEMBL28256508 0.84 TSHR (0.57) TSHRHSD17B10HTTMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111929392-B Method for analyzing N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof by pre-column derivatization 吉林医药学院 2023-11-14 CN claimed
CN-116023320-A 3- (N-p-toluenesulfonyl-L-alanyloxy) indole with polymorphic structure, and preparation method and application thereof 长春百纯和成医药科技有限公司 2023-04-28 CN claimed
CN-115872919-A Method for crystallizing 3- (N-p-toluenesulfonyl-L-alanyloxy) indole 吉林医药学院 2023-03-31 CN claimed
CN-111929392-A Method for pre-column derivatization analysis of N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof 吉林医药学院 2020-11-13 CN claimed
CN-111929392-B Method for analyzing N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof by pre-column derivatization 吉林医药学院 2023-11-14 CN disclosed
CN-111929392-B Method for analyzing N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof by pre-column derivatization 吉林医药学院 2023-11-14 CN disclosed
CN-111929392-B Method for analyzing N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof by pre-column derivatization 吉林医药学院 2023-11-14 CN disclosed
CN-116023320-A 3- (N-p-toluenesulfonyl-L-alanyloxy) indole with polymorphic structure, and preparation method and application thereof 长春百纯和成医药科技有限公司 2023-04-28 CN disclosed
CN-115872919-A Method for crystallizing 3- (N-p-toluenesulfonyl-L-alanyloxy) indole 吉林医药学院 2023-03-31 CN disclosed
CN-111929392-A Method for pre-column derivatization analysis of N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof 吉林医药学院 2020-11-13 CN disclosed
CN-111929392-A Method for pre-column derivatization analysis of N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof 吉林医药学院 2020-11-13 CN disclosed
CN-111929392-A Method for pre-column derivatization analysis of N- (p-toluenesulfonyl) -L-alanyl chloride and enantiomer thereof 吉林医药学院 2020-11-13 CN disclosed
EP-1378507-B1 Process for producing optically active imidazole derivatives, intermediates and synthesis thereof MITSUBISHI PHARMA CORP (JP) 2006-08-23 EP disclosed
EP-1378507-A2 Process for producing optically active imidazole compounds, intermediates for synthesizing the same, and process for producing the same Mitsubishi Pharma Corporation (JP) 2004-01-07 EP disclosed
CN-1133623-C Process for producing optically active imidazole compound, intermediate for synthesis thereof, and process for producing the same ������ҩ��ʽ���� 2004-01-07 CN disclosed
US-6166221-A Production method of optically active imidazole compound, synthetic intermediate therefor and production method thereof YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2000-12-26 US disclosed
US-6066739-A Process for producing optically active imidazole compounds, intermediates for synthesizing the same, and process for producing the same YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2000-05-23 US disclosed
CN-1251093-A Process for producing optically active imidazole compound, intermediates for synthesizing same YOSHITOMI PHARMACEUTICAL (JP) 2000-04-19 CN disclosed
EP-0972768-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE IMIDAZOLE COMPOUNDS, INTERMEDIATES FOR SYNTHESIZING THE SAME, AND PROCESS FOR PRODUCING THE SAME YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 2000-01-19 EP disclosed
US-3931218-A HYPOGLYCEMIC ANTIRESERPINE, ANTIULCER, OGENIC, ANTIARRHYTHMIA AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US disclosed