Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.55 |
| ▸ | MMP9 | P14780 | 4/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.55 |
| ▸ | MMP13 | P45452 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | MMP7 | P09237 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889040 | 0.85 | TSHR (0.58) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL25269775 | 0.85 | TSHR (0.58) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL7138463 | 0.85 | TSHR (0.58) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL791357 | 0.84 | ADAMTS4 (0.61) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL3687103 | 0.84 | ADAMTS4 (0.61) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL19000605 | 0.84 | TSHR (0.61) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL698908 | 0.84 | ADAMTS4 (0.71) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL4975578 | 0.84 | ADAMTS4 (0.71) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL698907 | 0.84 | ADAMTS4 (0.71) | SLC1A3SLC1A2SLC1A1TSHRHTT | |
| SCHEMBL28256508 | 0.84 | TSHR (0.57) | SLC1A3SLC1A2SLC1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907352-A2 | NOVEL DERIVATIVES OF AMINO ACIDS FOR TREATMENT OF OBESITY AND RELATED DISORDERS | Bexel Pharmaceuticals Inc (US) | 2008-04-09 | — | — | EP | claimed |
| WO-2007005774-A9 | NOVEL DERIVATIVES OF AMINO ACIDS FOR TREATMENT OF OBESITY AND RELATED DISORDERS | BEXEL PHARMACEUTICALS INC (US) | 2007-03-08 | — | — | WO | claimed |
| WO-2007005774-A2 | NOVEL DERIVATIVES OF AMINO ACIDS FOR TREATMENT OF OBESITY AND RELATED DISORDERS | BEXEL PHARMACEUTICALS, INC. (US) | 2007-01-11 | — | — | WO | claimed |
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |
| CN-101253146-A | Novel amino acid derivatives for the treatment of obesity and related disorders | BEXEL PHARMACEUTICALS INC (US) | 2008-08-27 | — | — | CN | disclosed |