Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.42 |
| ▸ | LTK | P29376 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CDK8 | P49336 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL5076892 | 0.92 | KDM4E (0.65) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| Fluorene SCHEMBL6009482 | 0.92 | KDM4E (0.65) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| Fluorene SCHEMBL28952566 | 0.89 | ALDH1A1 (0.62) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL29556700 | 0.86 | RAB9A (1.00) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL2362632 | 0.86 | RAB9A (0.84) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL225901 | 0.86 | RAB9A (1.00) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| SCHEMBL23989284 | 0.86 | RAB9A (1.00) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| Fluorene SCHEMBL29478468 | 0.86 | MAOA (0.68) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| Fluorene SCHEMBL31388525 | 0.86 | MAOA (0.68) | MAPTKDM4ELMNASMN1; SMN2NPC1 | |
| Fluorene SCHEMBL29355380 | 0.86 | MAOA (0.68) | MAPTKDM4ELMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912003-A | A kind of diacid monomer and its preparation method and application containing asymmetric fluorophore structure | 吉林大学 | 2018-11-30 | — | — | CN | claimed |
| CN-108863824-A | A kind of diamine monomer and its preparation method and application containing asymmetric fluorophore structure | 吉林大学 | 2018-11-23 | — | — | CN | claimed |
| CN-108912003-A | A kind of diacid monomer and its preparation method and application containing asymmetric fluorophore structure | 吉林大学 | 2018-11-30 | — | — | CN | disclosed |
| CN-108863824-A | A kind of diamine monomer and its preparation method and application containing asymmetric fluorophore structure | 吉林大学 | 2018-11-23 | — | — | CN | disclosed |