Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.38 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.38 |
| ▸ | USP25 | Q9UHP3 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212119 | 0.87 | NCF1 (0.45) | HTR6HTR7HTR4NCF1HTR3E | |
| Tert-Butyl Formate SCHEMBL28840344 | 0.86 | HTR6 (0.48) | HTR6HTR7HTR4HTR3EHTR3B | |
| Tert-Butyl Formate SCHEMBL28255190 | 0.77 | HTR6 (0.36) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28258169 | 0.76 | SLC6A4 (0.38) | HTR6DRD2RBP4 | |
| Tert-Butyl Formate SCHEMBL27944991 | 0.76 | MAPT (0.39) | HTR6USP28USP25ADRB1MAPT | |
| Tert-Butyl Formate SCHEMBL27621449 | 0.75 | KDR (0.41) | HTR6HTR7HTR3EHTR3BADRB1 | |
| SCHEMBL29707350 | 0.75 | BACE1 (0.50) | LMNAMAPTRBP4 | |
| SCHEMBL19212185 | 0.75 | BACE1 (0.50) | LMNAMAPTRBP4 | |
| Tert-Butyl Formate SCHEMBL27859337 | 0.74 | ADRB1 (0.47) | HTR6HTR3EHTR3BADRB1HTR3A | |
| Tert-Butyl Formate SCHEMBL28112679 | 0.74 | HTR6 (0.44) | HTR6HTR7HTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-A | Thienopyridine formamide as ubiquitin-specific protease inhibitor | 福马治疗股份有限公司 | 2018-12-21 | — | — | CN | disclosed |