Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.48 |
| ▸ | HTR3B | O95264 | 3/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190135 | 0.87 | HTR6 (0.61) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL28258283 | 0.86 | HTR6 (0.38) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL28334261 | 0.85 | HTR3A (0.48) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL28258175 | 0.78 | CHRNB2 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Tert-Butyl Formate SCHEMBL27859337 | 0.78 | ADRB1 (0.47) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL28112679 | 0.78 | HTR6 (0.44) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL27621449 | 0.77 | KDR (0.41) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL27824904 | 0.76 | ADRB1 (0.50) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL25389058 | 0.76 | NCF1 (0.74) | HTR6DRD3HTR7 | |
| SCHEMBL14009665 | 0.76 | HTR3E (0.68) | HTR6HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459044-A | Tank-binding kinase inhibitor compounds | 吉利德科学公司 | 2017-02-22 | — | — | CN | disclosed |