Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377280 | 0.79 | ENPP2 (0.38) | CES2CES1 | |
| SCHEMBL24109422 | 0.76 | CA12 (0.36) | CA12CA1CA9ORAI1ORAI2 | |
| SCHEMBL2316506 | 0.76 | ORAI1 (0.54) | CA1CA9ORAI1ORAI2ORAI3 | |
| SCHEMBL4272057 | 0.73 | CA12 (0.33) | CA12CA1CA9ORAI1ORAI2 | |
| SCHEMBL6246558 | 0.71 | TRPV6 (0.52) | CA12CA1CA9ORAI1ORAI2 | |
| SCHEMBL124847 | 0.71 | CA1 (0.45) | CA12CA1CA9ORAI1ORAI2 | |
| SCHEMBL16812679 | 0.67 | CA12 (0.41) | CA12CA1CA9ORAI1ORAI2 | |
| SCHEMBL2318155 | 0.66 | CES2 (0.36) | CA9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL7706033 | 0.66 | CA12 (0.38) | CA12CA1CA9CES2CES1 | |
| SCHEMBL244920 | 0.65 | TRPV6 (0.50) | CA1ORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071554-A | Pyrazolo [1,5-a ] pyrimidine compounds | 卫材R&D管理有限公司 | 2018-12-21 | — | — | CN | disclosed |