Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | ARG1 | P05089 | 1/20 | 0.52 |
| ▸ | ARG2 | P78540 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28256892 | 0.92 | ABL1 (0.54) | ABL1RIN1ARG1ARG2OPRM1 | |
| SCHEMBL28256826 | 0.91 | ARG1 (0.53) | ABL1RIN1ARG1ARG2SIGMAR1 | |
| SCHEMBL28258433 | 0.88 | ACHE (0.52) | ABL1RIN1SIGMAR1ACHE | |
| SCHEMBL28258405 | 0.87 | ALDH1A1 (0.53) | OPRM1SIGMAR1 | |
| SCHEMBL28256920 | 0.87 | ARG1 (0.56) | ABL1RIN1ARG1ARG2SIGMAR1 | |
| SCHEMBL28256965 | 0.85 | CCR3 (0.47) | ABL1RIN1 | |
| SCHEMBL28256889 | 0.84 | ALDH1A1 (0.53) | ABL1RIN1ARG1ARG2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28256857 | 0.84 | TSHR (0.50) | ABL1RIN1ACHEBCHE | |
| SCHEMBL28258434 | 0.83 | ACHE (0.52) | ABL1RIN1OPRM1SIGMAR1ACHE | |
| Hydrochloric Acid SCHEMBL28258438 | 0.83 | CHRM3 (0.47) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876955-B | Arginase inhibitor and its treatment use | 马尔斯公司 | 2018-11-23 | — | — | CN | disclosed |