Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28258397 | 0.87 | ABL1 (0.60) | OPRM1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28256892 | 0.82 | ABL1 (0.54) | KDM4EOPRM1SIGMAR1 | |
| SCHEMBL28258363 | 0.80 | SPHK1 (0.41) | ALDH1A1CYP2J2HRH1OPRM1CYP3A4 | |
| SCHEMBL28258433 | 0.78 | ACHE (0.52) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL28256826 | 0.78 | ARG1 (0.53) | MEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL28258448 | 0.76 | ARG1 (0.51) | CYP2J2HRH1KCNH2BLM | |
| SCHEMBL28258434 | 0.76 | ACHE (0.52) | ALDH1A1KDM4EMEN1TSHRKMT2A | |
| SCHEMBL28256965 | 0.76 | CCR3 (0.47) | MEN1 | |
| SCHEMBL10265453 | 0.75 | ARG1 (0.63) | ALDH1A1HRH1KCNH2SIGMAR1BLM | |
| SCHEMBL28256889 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876955-B | Arginase inhibitor and its treatment use | 马尔斯公司 | 2018-11-23 | — | — | CN | disclosed |