Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29073823 | 0.87 | ALOX15 (0.38) | TSHRSMN1; SMN2CA1CA2MMP1 | |
| SCHEMBL28316943 | 0.85 | CA1 (0.49) | CA1CA2MMP2MMP13SLC6A2 | |
| SCHEMBL28283507 | 0.80 | SLC6A2 (0.36) | SLC6A2SLC6A4SSTR4 | |
| SCHEMBL27370620 | 0.79 | CTSB (0.41) | SLC6A2SLC6A4CTSBSSTR4 | |
| SCHEMBL6749403 | 0.79 | GAA (0.41) | CA1CA2SLC6A2SLC6A4CA12 | |
| SCHEMBL6745832 | 0.79 | CTSB (0.38) | SLC6A2SLC6A4CTSBSSTR4 | |
| SCHEMBL5175530 | 0.79 | CTSB (0.38) | SLC6A2SLC6A4CTSBSSTR4 | |
| SCHEMBL3963174 | 0.78 | CTSB (0.41) | SLC6A2SLC6A4CTSBSSTR4 | |
| SCHEMBL6422590 | 0.78 | SLC6A2 (0.38) | SLC6A2SLC6A4 | |
| SCHEMBL29266288 | 0.75 | SSTR4 (0.39) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110015984-A | Substituted (E)-N '-(1- phenylethylene) benzoyl hydrazine analog as histone demethylase inhibitor | 犹他大学研究基金会 | 2019-07-16 | — | — | CN | disclosed |
| CN-105555784-B | Substituted (E) -N' - (1-phenylethylene) benzoyl hydrazine analogs as histone demethylase inhibitors | 犹他大学研究基金会 | 2019-03-15 | — | — | CN | disclosed |
| CN-105985265-B | Indenes -1- subunit sulfonyl benzoyl hydrazine derivatives and its preparation method and application | 四川大学 | 2018-11-13 | — | — | CN | disclosed |