SCHEMBL27370620

SCHEMBL27370620

Cc1ccccc1S(=O)(=O)C1CNCCO1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSB P07858 1/20 0.41
SLC6A2 P23975 3/20 0.40
SLC6A4 P31645 3/20 0.40
SLC6A3 Q01959 3/20 0.40
PKM P14618 1/20 0.40
SSTR4 P31391 9/20 0.40
ADRB2 P07550 1/20 0.38
HTR1A P08908 1/20 0.38
HTR2A P28223 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
ADRA2C P18825 1/20 0.38
HTR6 P50406 2/20 0.36
CASP6 P55212 1/20 0.36
SSTR1 P30872 1/20 0.35
SSTR2 P30874 1/20 0.35
SSTR3 P32745 1/20 0.35
SSTR5 P35346 1/20 0.35
HTR2C P28335 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175530 0.82 CTSB (0.38) CTSBSLC6A2SLC6A4SLC6A3SSTR4
SCHEMBL6749403 0.82 GAA (0.41) CTSBSLC6A2SLC6A4SLC6A3SSTR4
SCHEMBL6745832 0.82 CTSB (0.38) CTSBSLC6A2SLC6A4SLC6A3SSTR4
SCHEMBL3963174 0.82 CTSB (0.41) CTSBSLC6A2SLC6A4SLC6A3SSTR4
SCHEMBL28258693 0.79 TSHR (0.42) CTSBSLC6A2SLC6A4SSTR4
SCHEMBL6422590 0.78 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3ADRB2HTR1A
SCHEMBL6749626 0.78 KMT2A (0.46) PKM
SCHEMBL27721958 0.77 CTSB (0.64) CTSBPKMHTR2AHTR2C
SCHEMBL9518473 0.76 SSTR4 (0.40) SLC6A2SLC6A4SLC6A3PKMSSTR4
SCHEMBL28433779 0.76 HTR6 (0.39) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1064594-C Polymeric film AMERICAN DUPONT TEZY FILM L P (US) 2001-04-18 CN disclosed
CN-1139406-A Polymer film ICI PLC (GB) 1997-01-01 CN disclosed