SCHEMBL28259014

SCHEMBL28259014

C#Cc1ccc(-c2nc(-c3ccc(C#C)cc3)nc(-c3ccc(C#C)cc3)n2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.46
KEAP1 Q14145 1/20 0.45
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
EGLN2 Q96KS0 1/20 0.38
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
HDAC6 Q9UBN7 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ABCG2 Q9UNQ0 1/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A1 P04798 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15090268 0.91 L3MBTL1 (0.50) HDAC8KEAP1MAOAMAOBL3MBTL1
SCHEMBL10937156 0.91 L3MBTL1 (0.50) HDAC8KEAP1MAOAMAOBL3MBTL1
SCHEMBL13845115 0.81 KEAP1 (0.37) HDAC8KEAP1CA12CA1CA2
SCHEMBL139848 0.80 HDAC8 (0.50) HDAC8KEAP1CA12CA1CA2
SCHEMBL139611 0.80 HDAC8 (0.50) HDAC8KEAP1CA12CA1CA2
Water SCHEMBL11190539 0.77 HDAC8 (0.48) HDAC8KEAP1CA12CA1CA2
SCHEMBL10481156 0.77 HDAC8 (0.48) HDAC8KEAP1CA12CA1CA2
SCHEMBL28468320 0.77 HDAC8 (0.44) HDAC8KEAP1CA12CA1CA2
SCHEMBL22735833 0.77 TP53 (0.48) HDAC8KEAP1CA12CA1CA2
SCHEMBL28871 0.76 HDAC8 (0.59) HDAC8KEAP1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842054-B Preparation method of conjugated microporous polymer solid-phase extraction membrane material and application of conjugated microporous polymer solid-phase extraction membrane material in detection of benzoyl urea pesticides 山东省计量科学研究院 2025-06-13 CN claimed
CN-119842054-A Preparation method of conjugated microporous polymer solid-phase extraction membrane material and application of conjugated microporous polymer solid-phase extraction membrane material in detection of benzoyl urea pesticides 山东省计量科学研究院 2025-04-18 CN claimed
CN-119819275-A Multifunctional site porous aromatic framework adsorbent for adsorbing trace iodine and preparation method thereof 海南大学 2025-04-15 CN claimed
CN-119633783-A Pretreatment method and analysis application of quinolone antibiotics sample 山东省分析测试中心 2025-03-18 CN claimed
CN-119285971-A Trinuclear silver-carbon metal organic framework compound and preparation method and application thereof 西北工业大学 2025-01-10 CN claimed
CN-119118184-A Hexagonal Cu2S nano-sheet and Cu2Preparation method and application of S@COPs heterojunction material 南昌大学 2024-12-13 CN claimed
CN-118994540-A Conjugated microporous polymer with quinoxaline diol as recognition group, and preparation method and application thereof 广西民族师范学院 2024-11-22 CN claimed
CN-118325080-A Conjugated microporous organic polymer hollow sphere and preparation method and application thereof 上海大学 2024-07-12 CN claimed
CN-118231717-A Azacyclic porous aromatic skeleton composite high-temperature proton exchange membrane, preparation method and application 东北师范大学 2024-06-21 CN claimed
CN-117443361-A Material for adsorbing dye wastewater 榆林学院 2024-01-26 CN claimed
CN-116751363-A Preparation method and application of nitrogen-oxygen functionalized porous aromatic framework material 辽宁大学 2023-09-15 CN claimed
CN-114920907-B Aminated porous aromatic skeleton compound and preparation method and application thereof 福建农林大学 2023-06-20 CN claimed
CN-113831512-B Polynitrogen conjugated microporous polymer and preparation method and application thereof 中山大学 2023-03-24 CN claimed
CN-114920907-A Aminated porous aromatic skeleton compound and preparation method and application thereof 福建农林大学 2022-08-19 CN claimed
CN-114653344-A Triazole gel material, preparation method thereof and application of triazole gel material in adsorption of organic pollutants 中山大学 2022-06-24 CN claimed
CN-110982046-B Tetraphenyl ethylene-based conjugated microporous polymer aggregation-induced electrochemical luminescence sensor and preparation method and application thereof 山东师范大学 2022-05-27 CN claimed
EP-3959763-A1 RECHARGEABLE LITHIUM-ION BATTERY ANODE, AND METHOD FOR PRODUCING A RECHARGEABLE LITHIUM-ION BATTERY ANODE Humboldt-Universität zu Berlin (DE) 2022-03-02 EP claimed
CN-110982046-A Tetraphenyl ethylene-based conjugated microporous polymer aggregation-induced electrochemical luminescence sensor and preparation method and application thereof 山东师范大学 2020-04-10 CN claimed
CN-109174185-A A kind of titanium doped type ternary metal organic framework material and preparation method thereof 武汉绿帆世纪科技有限公司 2019-01-11 CN claimed
CN-109161029-A A kind of ternary metal organic framework material and preparation method thereof 武汉绿帆世纪科技有限公司 2019-01-08 CN claimed