Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505552 | 0.90 | ALDH1A1 (0.66) | ALDH1A1CYP1A2GAAHPGDTARBP2 | |
| SCHEMBL3114653 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP1A2GAAHPGDTARBP2 | |
| SCHEMBL1431060 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP1A2GAAHPGDTSHR | |
| SCHEMBL10666288 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP1A2GAAHPGDTSHR | |
| SCHEMBL15251297 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP1A2GAAHPGDTARBP2 | |
| SCHEMBL16434159 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP1A2GAAHPGDTSHR | |
| SCHEMBL9861374 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2GAAHPGDTARBP2 | |
| SCHEMBL2826874 | 0.81 | GAA (0.55) | ALDH1A1CYP1A2GAAHPGDTARBP2 | |
| SCHEMBL2825407 | 0.81 | ALDH1A1 (0.82) | ALDH1A1CYP1A2GAAHPGDMAPT | |
| SCHEMBL16437812 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP1A2GAAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2226322-A1 | IMIDAZOLE CARBONYL COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2010-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | TOP1, TOP2B, TOP2A | ALDH1A1 3596/4885CYP1A2 2031/4885GAA 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.