SCHEMBL1505552

SCHEMBL1505552

CCOC(=O)c1nc(Cl)sc1C(=O)OCC

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
CYP1A2 P05177 1/20 0.66
MAPT P10636 3/20 0.47
TRPM8 Q7Z2W7 3/20 0.47
HPGD P15428 3/20 0.45
LMNA P02545 1/20 0.45
TSHR P16473 1/20 0.44
TARBP2 Q15633 1/20 0.44
GAA P10253 2/20 0.43
HSD17B10 Q99714 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CDC7 O00311 2/20 0.43
DBF4 Q9UBU7 2/20 0.43
KMT2A Q03164 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
MC4R P32245 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2826239 0.90 ALDH1A1 (0.54) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL1553063 0.90 ALDH1A1 (0.54) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL1553046 0.90 ALDH1A1 (0.54) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL3114653 0.89 ALDH1A1 (0.56) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL2826240 0.89 ALDH1A1 (0.53) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL1553583 0.86 ALDH1A1 (0.50) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL1554058 0.85 ALDH1A1 (0.49) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL187316 0.84 ALDH1A1 (0.59) ALDH1A1MAPTHPGDLMNATSHR
SCHEMBL2826874 0.84 GAA (0.55) ALDH1A1CYP1A2MAPTTRPM8HPGD
SCHEMBL9861374 0.84 ALDH1A1 (0.50) ALDH1A1CYP1A2MAPTTRPM8HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9583710-B2 Organic semiconductor polymer, composition for organic semiconductor material, and photovoltaic cell FUJIFILM CORPORATION (JP) 2017-02-28 US disclosed
US-9583710-B2 Organic semiconductor polymer, composition for organic semiconductor material, and photovoltaic cell FUJIFILM CORPORATION (JP) 2017-02-28 US disclosed
US-9246102-B2 Organic semiconductor polymer, composition for organic semiconductor material, and photovoltaic cell FUJIFILM CORPORATION (JP) 2016-01-26 US disclosed
US-9246102-B2 Organic semiconductor polymer, composition for organic semiconductor material, and photovoltaic cell FUJIFILM CORPORATION (JP) 2016-01-26 US disclosed
US-20140021456-A1 ORGANIC SEMICONDUCTOR POLYMER, COMPOSITION FOR ORGANIC SEMICONDUCTOR MATERIAL, AND PHOTOVOLTAIC CELL FUJIFILM CORPORATION (JP) 2014-01-23 US disclosed
US-20140021456-A1 ORGANIC SEMICONDUCTOR POLYMER, COMPOSITION FOR ORGANIC SEMICONDUCTOR MATERIAL, AND PHOTOVOLTAIC CELL FUJIFILM CORPORATION (JP) 2014-01-23 US disclosed
US-20140020762-A1 ORGANIC SEMICONDUCTOR POLYMER, COMPOSITION FOR ORGANIC SEMICONDUCTOR MATERIAL, AND PHOTOVOLTAIC CELL FUJIFILM CORPORATION (JP) 2014-01-23 US disclosed
US-20140020762-A1 ORGANIC SEMICONDUCTOR POLYMER, COMPOSITION FOR ORGANIC SEMICONDUCTOR MATERIAL, AND PHOTOVOLTAIC CELL FUJIFILM CORPORATION (JP) 2014-01-23 US disclosed
EP-1853586-B1 ANTIBACTERIAL PIPERIDINE DERIVATIVES ASTRAZENECA AB (SE) 2013-07-24 EP disclosed
US-20130150366-A1 CHEMICAL COMPOUNDS ASTRAZENECA, INTELLECTUAL PROPERTY (GB) 2013-06-13 US disclosed
US-20120101100-A1 HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 ASTRAZENECA AB (SE) 2012-04-26 US disclosed
WO-2011024004-A1 HETEROCYCLIC UREA DERIVATIVES USEFUL FOR TREATMENT OF BACTERIAL INFECTION ASTRAZENECA AB (SE) 2011-03-03 WO disclosed
EP-2262801-A1 HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 AstraZeneca AB (SE) 2010-12-22 EP disclosed
US-20100179150-A1 ANTIBACTERIAL PIPERDINE DERIVATIVES ASTRAZENECA AB (SE) 2010-07-15 US disclosed
WO-2009106885-A1 HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 ASTRAZENECA AB (SE) 2009-09-03 WO disclosed
EP-1853586-A1 ANTIBACTERIAL PIPERIDINE DERIVATIVES AstraZeneca AB (SE) 2007-11-14 EP disclosed
WO-2006087543-A1 ANTIBACTERIAL PIPERIDINE DERIVATIVES ASTRAZENECA AB (SE) 2006-08-24 WO disclosed
US-5284821-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US disclosed
US-5256633-A Applying pre or postemergence BASF AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5244867-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130150366-A1 CHEMICAL COMPOUNDS MRPL21, NISCH, CFTR ALDH1A1 419/4885CYP1A2 33/4885MAPT 2041/4885
US-20100179150-A1 ANTIBACTERIAL PIPERDINE DERIVATIVES PIR, HAMP, AMPD2 ALDH1A1 502/4885CYP1A2 602/4885MAPT 3374/4885
US-20120101100-A1 HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 UROD, UMPS, SLC14A1 ALDH1A1 1208/4885CYP1A2 143/4885MAPT 2015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.