Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263134 | 0.84 | KDM1A (0.37) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL19328932 | 0.72 | SLC6A3 (0.49) | SLC6A3HDAC2SLC6A2KDM4EALDH1A1 | |
| SCHEMBL28263132 | 0.68 | ABCB1 (0.44) | ALDH1A1 | |
| SCHEMBL1072730 | 0.68 | SLC6A3 (0.54) | SLC6A3HDAC2SLC6A2HTR2AHTR2C | |
| SCHEMBL20835816 | 0.68 | FFAR2 (0.43) | CHRNA7 | |
| SCHEMBL27410715 | 0.68 | SLC6A3 (0.41) | SLC6A3HDAC2SLC6A2SLC6A4GID4 | |
| SCHEMBL24738322 | 0.66 | HTR2A (0.53) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL2916068 | 0.66 | HTR2A (0.53) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL28790737 | 0.65 | SLC6A3 (0.49) | SLC6A3HDAC2SLC6A2HTR2AHTR2C | |
| SCHEMBL27492442 | 0.64 | HTR2C (0.53) | SLC6A3SLC6A2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071457-A | Inhibitors of indoleamine 2, 3-dioxygenase | 荷兰转化研究中心有限责任公司 | 2018-12-21 | — | — | CN | disclosed |