Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136224 | 0.85 | HSD11B1 (0.40) | CTSVCTSLHSD11B1RAB9ASMN1; SMN2 | |
| SCHEMBL7075862 | 0.81 | CTSV (0.45) | CTSVCTSLHSD11B1RAB9ASMN1; SMN2 | |
| SCHEMBL7077143 | 0.81 | CTSV (0.45) | CTSVCTSLHSD11B1RAB9ASMN1; SMN2 | |
| SCHEMBL27979090 | 0.79 | ADORA2A (0.39) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL28150568 | 0.79 | ALDH1A1 (0.36) | SMN1; SMN2TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL30140861 | 0.79 | ALDH1A1 (0.36) | SMN1; SMN2TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL27937638 | 0.77 | PDE9A (0.36) | CTSVCTSLRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29906503 | 0.77 | PDE9A (0.36) | CTSVCTSLRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL19410763 | 0.76 | HSD11B1 (0.43) | CTSVCTSLHSD11B1RAB9ASMN1; SMN2 | |
| SCHEMBL15391193 | 0.74 | KDM4E (0.38) | CTSVCTSLHSD11B1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311844-A | Triaizine compounds, its manufacturing method and the organic electroluminescent device as constituent | 东曹株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-105308026-B | Cyclic azine compound, manufacturing method with adamantyl and using the compound as the organic electroluminescent device of constituent | 东曹株式会社 | 2018-12-21 | — | — | CN | disclosed |