Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077143 | 1.00 | CTSV (0.45) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL7648614 | 0.82 | LTA4H (0.44) | CTSVCTSLRARBTSHRALDH1A1 | |
| SCHEMBL28263371 | 0.81 | CTSV (0.38) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL27752304 | 0.80 | CTSV (0.48) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL5418521 | 0.80 | CTSV (0.52) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL16678699 | 0.76 | HSD11B1 (0.63) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL10491604 | 0.76 | HSD11B1 (0.55) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL10491901 | 0.76 | HSD11B1 (0.55) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL19410763 | 0.74 | HSD11B1 (0.43) | CTSVCTSLRARBHSD11B1HSD17B10 | |
| SCHEMBL14314928 | 0.73 | KDM4E (0.49) | CTSVCTSLRARBHSD11B1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003516422-A | — | — | 2003-05-13 | — | — | JP | claimed |
| EP-1240272-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | THE UNIVERSITY OF LEEDS (GB) | 2002-09-18 | — | — | EP | claimed |
| WO-2001042391-A2 | A NEW FAMILY OF CONDUCTING LIQUID CRYSTALS | UNIVERSITY OF LEEDS (GB) | 2001-06-14 | — | — | WO | claimed |