Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290215 | 0.81 | MAOB (0.43) | PTPN1ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL31456561 | 0.81 | ALDH1A1 (0.66) | PTPN1ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL14788638 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL14901086 | 0.72 | ALDH1A1 (0.46) | PTPN1ALDH1A1KDM4EHPGDHNF4A | |
| SCHEMBL332581 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHNF4AALOX15 | |
| SCHEMBL24818258 | 0.71 | ALDH1A1 (0.40) | PTPN1ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL3978711 | 0.71 | PTPN1 (0.49) | PTPN1ALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL70098 | 0.70 | HNF4A (0.63) | ALDH1A1KDM4EHPGDHNF4AALOX15 | |
| SCHEMBL24318541 | 0.69 | ALDH1A1 (0.39) | PTPN1ALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL27987065 | 0.69 | NQO1 (0.42) | PTPN1ALDH1A1HPGDPOLBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108976186-A | A method of the four substituted furan class compound of preparation based on carbon-hydrogen link activation | 中国科学院大连化学物理研究所 | 2018-12-11 | — | — | CN | disclosed |