SCHEMBL28290215

SCHEMBL28290215

O=C(O)c1coc(C(=O)O)c1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.43
HNF4A P41235 3/20 0.43
ALDH1A1 P00352 3/20 0.43
ALOX15 P16050 1/20 0.43
PTPN1 P18031 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.39
PIM1 P11309 1/20 0.39
GFER P55789 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ACMSD Q8TDX5 3/20 0.39
DHFR P00374 1/20 0.39
MCL1 Q07820 1/20 0.39
CDC25B P30305 1/20 0.39
ATM Q13315 1/20 0.39
FABP4 P15090 3/20 0.38
FABP3 P05413 1/20 0.38
FABP5 Q01469 1/20 0.38
HPGD P15428 2/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2097892 0.81 HNF4A (0.43) HNF4AALDH1A1ALOX15PTPN1KDM4E
SCHEMBL28264016 0.81 PTPN1 (0.47) MAOBHNF4AALDH1A1ALOX15PTPN1
SCHEMBL8861328 0.79 FABP4 (0.41) HNF4AALDH1A1PTPN1KDM4EMAPT
SCHEMBL28752673 0.77 KMT2A (0.37) ALDH1A1PTPN1KDM4EMAPTFABP4
SCHEMBL27624418 0.75 PTPN1 (0.36) HNF4AALDH1A1PTPN1KDM4EMAPT
SCHEMBL1660355 0.75 KMT2A (0.36) ALDH1A1PTPN1KDM4EHPGDSMN1; SMN2
SCHEMBL27624327 0.73 ACVR1 (0.43) ALDH1A1PTPN1MAPTSMN1; SMN2
SCHEMBL71486 0.73 PTPN1 (0.46) HNF4AALDH1A1ALOX15PTPN1KDM4E
SCHEMBL332581 0.72 ALDH1A1 (0.57) HNF4AALDH1A1ALOX15KDM4EMAPT
SCHEMBL3978711 0.71 PTPN1 (0.49) ALDH1A1ALOX15PTPN1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608420-A A method of functionalization 1,3- butadiene is synthesized based on biomass chemicals 中国科学院长春应用化学研究所 2019-04-12 CN claimed
CN-109608420-A A method of functionalization 1,3- butadiene is synthesized based on biomass chemicals 中国科学院长春应用化学研究所 2019-04-12 CN disclosed