SCHEMBL332581

SCHEMBL332581

O=C(O)c1ccc(C(=O)O)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
ALOX15 P16050 1/20 0.57
WDR5 P61964 1/20 0.56
HNF4A P41235 3/20 0.54
ACMSD Q8TDX5 2/20 0.54
KDM4E B2RXH2 3/20 0.50
CYP1A2 P05177 1/20 0.50
DHFR P00374 1/20 0.48
MCL1 Q07820 1/20 0.48
CDC25B P30305 1/20 0.48
ATM Q13315 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HMGB1 P09429 1/20 0.48
HPGD P15428 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901069 0.95 ACMSD (0.61) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL9756514 0.89 WDR5 (0.47) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL9152464 0.89 ACMSD (0.55) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL12006684 0.89 HNF4A (0.55) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL70098 0.87 HNF4A (0.63) ALDH1A1ALOX15WDR5HNF4AACMSD
Salicylic Acid SCHEMBL5703937 0.87 ALDH1A1 (0.72) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL5820920 0.87 FABP3 (0.54) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL8422568 0.87 CYP3A4 (0.54) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL6755748 0.86 WDR5 (0.48) ALDH1A1ALOX15WDR5HNF4AACMSD
SCHEMBL30395913 0.86 WDR5 (0.48) ALDH1A1ALOX15WDR5HNF4AACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 615 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4299689-A2 COMPOSITIONS COMPRISING 1,2-DICHLORO-1,2-DIFLUOROETHYLENE FOR USE IN HEAT TRANSFER APPLICATIONS The Chemours Company FC, LLC (US) 2024-01-03 EP claimed
EP-3870667-B1 COMPOSITIONS CONTAINING DIFLUOROMETHANE, TETRAFLUOROPROPENE, AND CARBON DIOXIDE AND USES THEREOF CHEMOURS CO FC LLC (US) 2023-12-20 EP claimed
CN-115975602-B Non-combustible mixed refrigerant suitable for low-temperature system 北京星宇环试科技有限公司 2023-06-30 CN claimed
CN-115975602-A Non-combustible mixed refrigerant suitable for low-temperature system 北京星宇环试科技有限公司 2023-04-18 CN claimed
US-11359123-B2 Compositions containing difluoromethane, tetrafluoropropene, and carbon dioxide and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2022-06-14 US claimed
US-11339315-B2 Non-combustible mixed refrigerant having low greenhouse effect and application thereof JIANGXI TIANYU CHEMICAL CO., LTD. (CN) 2022-05-24 US claimed
US-11312891-B2 Refrigerant mixtures comprising difluoromethane, pentafluoroethane, tetrafluoroethane, tetrafluoropropene, and carbon dioxide and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2022-04-26 US claimed
CN-110343509-B Non-combustible mixed refrigerant capable of reducing greenhouse effect and application thereof 江西天宇化工有限公司 2021-09-14 CN claimed
US-20210198546-A1 NON-FLAMMABLE MIXED REFRIGERANT CAPABLE OF REDUCING GREENHOUSE EFFECT AND USE THEREOF JIANGXI TIANYU CHEMICAL CO., LTD. (CN) 2021-07-01 US claimed
US-20210179909-A1 COMPOSITIONS CONTAINING DIFLUOROMETHANE, TETRAFLUOROPROPENE, AND CARBON DIOXIDE AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-06-17 US claimed
EP-0401604-A1 Color minimization during melt preparation of polyamides GENERAL ELECTRIC COMPANY (US) 1990-12-12 EP claimed
EP-0379731-A1 Polyamides derived from toluenediamine GENERAL ELECTRIC COMPANY (US) 1990-08-01 EP claimed
EP-0184594-B1 PROCESS FOR THE PREPARATION OF POLAYMIDES BY AMIDE-ESTER INTERCHANGE GENERAL ELECTRIC COMPANY (US) 1989-11-23 EP claimed
EP-0035895-B1 SEMI OR FULLY CONTINUOUS PROCESS FOR PREPARATION OF POLYESTER BY TRANSESTERIFICATION POLYMERIZATION CELANESE CORPORATION (US) 1985-09-11 EP claimed
EP-0035897-B1 PROCESS FOR PREPARATION OF LINEAR AROMATIC POLYESTER BY TRANSESTERIFICATION POLYMERIZATION OCCIDENTAL CHEMICAL CORPORATION (US) 1985-02-13 EP claimed
EP-0044509-B1 PROCESS FOR PREPARING DIPHENYL ISOPHTHALATE AND DIPHENYL TEREPHTHALATE GENERAL ELECTRIC COMPANY (US) 1984-06-06 EP claimed
EP-0044510-B1 PROCESS FOR THE PREPARATION OF DIARYL ESTERS GENERAL ELECTRIC COMPANY (US) 1984-03-07 EP claimed
US-4272586-A HAVING A BONDING LAYER OF A PHOTOCURED MIXTURE OF A POLYENE, A POLYTHIOL, A PHOTOINIATOR, AND A SILICON-CONTAINING ANCHORING AGENT; OPTICAL LENSES; CARS DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-06-09 US claimed
EP-0002218-B1 PROCESS FOR THE PREPARATION OF AROMATIC POLYESTERS BAYER AG (DE) 1980-07-23 EP claimed
EP-0002218-A1 Process for the preparation of aromatic polyesters BAYER AG (DE) 1979-06-13 EP claimed