Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27864466 | 0.88 | TRPM8 (0.34) | TRPM8SLC6A3RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL177681 | 0.78 | — | — | |
| Ethoxycarbonyl Group SCHEMBL28264141 | 0.78 | TRPM8 (0.32) | TRPM8RAB9ANPC1SMN1; SMN2 | |
| Ethoxycarbonyl Group SCHEMBL28602754 | 0.77 | — | — | |
| Thiazole-5-Carbaldehyde SCHEMBL28826551 | 0.77 | PIM1 (0.33) | — | |
| Bromide SCHEMBL4849534 | 0.76 | — | — | |
| SCHEMBL4974945 | 0.75 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27880657 | 0.75 | SLC6A3 (0.32) | SLC6A3 | |
| Ethoxycarbonyl Group SCHEMBL27864435 | 0.75 | CYP11B1 (0.38) | CYP3A4 | |
| SCHEMBL27548446 | 0.73 | RAB9A (0.36) | SLC6A3RAB9ANPC1SMN1; SMN2PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071504-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2018-12-21 | — | — | CN | disclosed |