Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27880657 | 0.79 | SLC6A3 (0.32) | — | |
| Ethoxycarbonyl Group SCHEMBL28264137 | 0.78 | TRPM8 (0.35) | TRPM8NPC1RAB9ASMN1; SMN2 | |
| Ethoxycarbonyl Group SCHEMBL27864466 | 0.76 | TRPM8 (0.34) | TRPM8NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL47203 | 0.76 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27667512 | 0.71 | KDM4E (0.31) | — | |
| Pyrazine SCHEMBL27608305 | 0.69 | KMT2A (0.31) | — | |
| Ethoxycarbonyl Group SCHEMBL1332384 | 0.68 | — | — | |
| Ethoxycarbonyl Group SCHEMBL453 | 0.68 | — | — | |
| Ethoxycarbonyl Group SCHEMBL5306888 | 0.68 | ALDH1A1 (0.38) | — | |
| SCHEMBL4974945 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071504-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2018-12-21 | — | — | CN | disclosed |