Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | QDPR | P09417 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334911 | 1.00 | CA2 (0.51) | CA2NR3C1QDPRTSHRALOX5 | |
| SCHEMBL2826447 | 0.86 | KDM1A (0.51) | NR3C1ALDH1A1GAAKDM1A | |
| SCHEMBL1380700 | 0.86 | KDM1A (0.51) | NR3C1ALDH1A1GAAKDM1A | |
| SCHEMBL4260439 | 0.86 | KDM1A (0.51) | NR3C1ALDH1A1GAAKDM1A | |
| SCHEMBL1380697 | 0.86 | KDM1A (0.51) | NR3C1ALDH1A1GAAKDM1A | |
| SCHEMBL4263152 | 0.79 | KDM1A (0.44) | TSHRALDH1A1KDM1A | |
| SCHEMBL4259945 | 0.78 | KDM1A (0.51) | ALDH1A1MEN1GAAKMT2AKDM1A | |
| SCHEMBL4259946 | 0.78 | KDM1A (0.51) | ALDH1A1MEN1GAAKMT2AKDM1A | |
| SCHEMBL5054677 | 0.78 | KDM1A (0.51) | ALDH1A1MEN1GAAKMT2AKDM1A | |
| SCHEMBL8864091 | 0.78 | QDPR (0.69) | CA2NR3C1QDPRTSHRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166746-B2 | N-bisaryl- and n-aryl-cycloakylidenyl-αhydroxy-and α-alkoxy acid amides | SYNGENTA CROP PROTECTION, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20050245607-A1 | N-bisaryl- and n-aryl-cylcloakylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides | SYNGENTA CROP PROTECTION, INC. | 2005-11-03 | — | — | US | disclosed |
| EP-1534664-A1 | N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES | Syngenta Participations AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| US-20040214721-A1 | Novel n-bisaryl- and n-aryl-cycloalkylidenyl-alpha-sulfin- and alpha-sulfonamino acid amides | SYNGENTA CROP PROTECTION, INC. | 2004-10-28 | — | — | US | disclosed |
| CN-1520398-A | Novel N-isaryl-and N-aryl-cycloalkylidenyl-G(a)-sulfin-and G(a)-sulfonamino acid amides | �����ɷ� | 2004-08-11 | — | — | CN | disclosed |
| EP-1399418-A1 | NOVEL N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-$G(a)-SULFIN- AND $G(a)-SULFONAMINO ACID AMIDES | Syngenta Participations AG (CH) | 2004-03-24 | — | — | EP | disclosed |
| WO-2004011417-A1 | N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-05 | — | — | WO | disclosed |
| WO-2003002525-A1 | NOVEL N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-$G(a)-SULFIN- AND $G(a)-SULFONAMINO ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214721-A1 | Novel n-bisaryl- and n-aryl-cycloalkylidenyl-alpha-sulfin- and alpha-sulfonamino acid amides | ARSA, SFN, HCCS | CA2 514/4885NR3C1 912/4885QDPR 3242/4885 |
| US-20050245607-A1 | N-bisaryl- and n-aryl-cylcloakylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides | CBR3, CBR1, AKR1C3 | CA2 1478/4885NR3C1 1186/4885QDPR 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.