SCHEMBL28265349

SCHEMBL28265349

CN(C)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1N(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
GAA P10253 2/20 0.53
LMNA P02545 2/20 0.53
TSHR P16473 2/20 0.53
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP2C19 P33261 3/20 0.49
ALOX15 P16050 2/20 0.45
MAPK1 P28482 2/20 0.45
HTT P42858 2/20 0.45
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 2/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
G6PD P11413 1/20 0.44
PABPC1 P11940 1/20 0.44
KMT2A Q03164 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29393893 0.78 CYP2C19 (0.47) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL599369 0.78 CYP2C19 (0.47) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL3686863 0.75 ALDH1A1 (0.49) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL5072462 0.75 ALDH1A1 (0.58) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL11824508 0.72 ALDH1A1 (0.54) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL9416923 0.72 CYP2C19 (0.47) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL29442910 0.72 ALOX15 (0.60) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL4899794 0.72 ALOX15 (0.60) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL11002684 0.71 HSPA5 (0.68) ALDH1A1GAALMNATSHRCYP1A2
SCHEMBL15129714 0.71 ALDH1A1 (0.49) ALDH1A1GAALMNATSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134202-A The method that lignin cracking prepares 2,6 di tert butyl 4 methyl phenol 北京联合大学 2019-01-04 CN disclosed