Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129714 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP2C19GAATSHRLMNA | |
| SCHEMBL27388601 | 0.83 | ALDH1A1 (0.39) | ALDH1A1CYP2C19GAATSHRLMNA | |
| SCHEMBL10787272 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GAATSHRLMNACYP2D6 | |
| SCHEMBL10790211 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP2C19GAATSHRLMNA | |
| SCHEMBL10893525 | 0.81 | CA2 (0.46) | ALDH1A1CYP2C19GAATSHRLMNA | |
| SCHEMBL158900 | 0.81 | CA2 (0.46) | ALDH1A1CYP2C19GAATSHRLMNA | |
| SCHEMBL30697134 | 0.81 | CA2 (0.46) | ALDH1A1CYP2C19GAATSHRLMNA | |
| SCHEMBL430925 | 0.79 | CA2 (0.45) | ALDH1A1CYP2C19TSHRLMNACYP2D6 | |
| SCHEMBL3636222 | 0.79 | CA2 (0.45) | ALDH1A1CYP2C19TSHRLMNACYP2D6 | |
| SCHEMBL29539350 | 0.79 | CA2 (0.45) | ALDH1A1CYP2C19TSHRLMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4677154-A | Stabilizer package for polyurethane comprising a substituted cresol and another costabilizer | BASF CORPORATION (US) | 1987-06-30 | — | — | US | claimed |
| US-20180344693-A1 | STABILIZED STATIN FORMULATIONS | CUMBERLAND PHARMACEUTICALS INC. (US) | 2018-12-06 | — | — | US | disclosed |
| EP-1853660-B1 | STABILIZATION OF POLYOL OR POLYURETHANE COMPOSITIONS AGAINST THERMAL OXIDATION | BASF SE (DE) | 2010-06-23 | — | — | EP | disclosed |
| US-7541397-B2 | Uretonimine-modified isocyanate composition and method of forming the same | BASF CORPORATION (US) | 2009-06-02 | — | — | US | disclosed |
| US-20070213432-A1 | URETONIMINE-MODIFIED ISOCYANATE COMPOSITION AND METHOD OF FORMING THE SAME | BASF CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-7262319-B2 | Phenolic antioxidants in crystalline form | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-08-28 | — | — | US | disclosed |
| US-20060189820-A1 | Phenolic antioxidants in crystalline form | CIBA SPECIALTY CHEMICALS CORPORATION | 2006-08-24 | — | — | US | disclosed |
| US-6916960-B2 | Diol-functionalized antioxidant and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-07-12 | — | — | US | disclosed |
| US-20040192969-A1 | Diol-functionalized antioxidant and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2004-09-30 | — | — | US | disclosed |
| US-4677154-A | Stabilizer package for polyurethane comprising a substituted cresol and another costabilizer | BASF CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4677154-A | Stabilizer package for polyurethane comprising a substituted cresol and another costabilizer | BASF CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0116712-B1 | SYNTHESIS OF HINDERED PHENOLS | ETHYL CORPORATION (US) | 1987-03-25 | — | — | EP | disclosed |
| EP-0116712-A1 | Synthesis of hindered phenols | ETHYL CORPORATION (US) | 1984-08-29 | — | — | EP | disclosed |
| WO-1984002336-A1 | ANTIOXIDANT SYNTHESIS | ETHYL CORP (US) | 1984-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189820-A1 | Phenolic antioxidants in crystalline form | HAAO, PPOX, PNPO | ALDH1A1 763/4885CYP2C19 1730/4885GAA 3335/4885 |
| US-20180344693-A1 | STABILIZED STATIN FORMULATIONS | HMGCR, PCSK9, NPC1L1 | ALDH1A1 2830/4885CYP2C19 233/4885GAA 708/4885 |
| US-20040192969-A1 | Diol-functionalized antioxidant and process for preparation thereof | GPX1, GPX4, SOD1 | ALDH1A1 42/4885CYP2C19 1125/4885GAA 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.