Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 5/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 12/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671983 | 0.73 | PIK3R1 (0.41) | WDR5PIK3R1PIK3CAAR | |
| SCHEMBL23259495 | 0.69 | PIK3R1 (0.37) | PIK3R1PIK3CAAR | |
| SCHEMBL7699003 | 0.68 | AR (0.44) | PIK3R1PIK3CAAR | |
| SCHEMBL9730660 | 0.68 | PIK3R1 (0.38) | WDR5PIK3R1PIK3CAAR | |
| SCHEMBL7694139 | 0.68 | ADRA1A (0.50) | PIK3R1PIK3CAAR | |
| SCHEMBL7530896 | 0.68 | IDO1 (0.39) | RXFP1 | |
| SCHEMBL30761169 | 0.68 | AR (0.41) | AR | |
| SCHEMBL28294156 | 0.68 | NOTUM (0.41) | — | |
| SCHEMBL28265668 | 0.68 | MAP4K4 (0.35) | ARPIM1PIM3 | |
| SCHEMBL24018711 | 0.67 | PIK3R1 (0.38) | WDR5PIK3R1PIK3CAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | disclosed |