Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 9/20 | 0.48 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672495 | 0.78 | MKNK1 (0.52) | MKNK1MKNK2CYP1A2POLBCYP3A4 | |
| SCHEMBL30672492 | 0.76 | MAPT (0.48) | MKNK1MKNK2CYP1A2POLBCYP3A4 | |
| SCHEMBL29288019 | 0.76 | MAPT (0.48) | MKNK1MKNK2CYP1A2POLBCYP3A4 | |
| SCHEMBL30514275 | 0.70 | BCAT2 (0.67) | MKNK1MKNK2PKN1PKN2KMT2A | |
| SCHEMBL31227976 | 0.70 | BCAT2 (0.67) | MKNK1MKNK2PKN1PKN2KMT2A | |
| SCHEMBL167082 | 0.70 | BCAT2 (0.67) | MKNK1MKNK2PKN1PKN2KMT2A | |
| Hydrochloric Acid SCHEMBL27890957 | 0.68 | BCAT2 (0.65) | MKNK1MKNK2PKN1PKN2KMT2A | |
| Hydrochloric Acid SCHEMBL30165666 | 0.68 | BCAT2 (0.65) | MKNK1MKNK2PKN1PKN2KMT2A | |
| SCHEMBL28619699 | 0.68 | HTT (0.42) | MKNK1MKNK2MAPTALDH1A1 | |
| SCHEMBL9894437 | 0.68 | MAPT (0.50) | MKNK1MKNK2CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | disclosed |