Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672492 | 1.00 | MAPT (0.48) | MAPTMKNK1MKNK2ALDH1A1MEN1 | |
| SCHEMBL9894437 | 0.90 | MAPT (0.50) | MAPTMKNK1MKNK2ALDH1A1MEN1 | |
| SCHEMBL9893973 | 0.82 | NPC1 (0.59) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL30672495 | 0.80 | MKNK1 (0.52) | MAPTMKNK1MKNK2KMT2AG6PD | |
| SCHEMBL461803 | 0.78 | HTT (0.49) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL455086 | 0.78 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL9895124 | 0.77 | G6PD (0.41) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL28265682 | 0.76 | MKNK1 (0.48) | MAPTMKNK1MKNK2ALDH1A1MEN1 | |
| SCHEMBL29288018 | 0.75 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2AG6PD | |
| SCHEMBL30174246 | 0.71 | MKNK1 (0.47) | MAPTMKNK1MKNK2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109348715-A | pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2019-02-15 | — | — | CN | claimed |