Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28208232 | 0.83 | CES2 (0.41) | ALOX15CES2ALDH1A1RXRARXRB | |
| SCHEMBL27835356 | 0.83 | AKR1C4 (0.41) | ALDH1A1P2RX1TMPRSS4NOTUMP2RX4 | |
| SCHEMBL27964790 | 0.78 | CES2 (0.45) | ALOX15CES2CES1ALDH1A1P2RX1 | |
| SCHEMBL8103503 | 0.76 | CES2 (0.39) | ALOX15CES2CES1ALDH1A1P2RX1 | |
| SCHEMBL27835380 | 0.73 | CES2 (0.36) | ALOX15CES2CES1ALDH1A1NOTUM | |
| SCHEMBL28265638 | 0.72 | NOTUM (0.42) | ALOX15CES2CES1ALDH1A1NOTUM | |
| SCHEMBL42960 | 0.72 | DDR1 (0.44) | CES2ALDH1A1P2RX1TMPRSS4HPGD | |
| SCHEMBL20268801 | 0.72 | ALDH1A1 (0.47) | ALOX15CES2CES1ALDH1A1P2RX1 | |
| SCHEMBL27853419 | 0.70 | NOTUM (0.44) | ALOX15CES2CES1ALDH1A1NOTUM | |
| SCHEMBL28061682 | 0.70 | RAB9A (0.37) | CES2P2RX1TMPRSS4P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | disclosed |