Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | AXL | P30530 | 2/20 | 0.50 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | METTL3 | Q86U44 | 4/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260364 | 0.84 | NOS1 (0.52) | NOS1AXLKITIDO1METAP2 | |
| SCHEMBL30285533 | 0.84 | NOS1 (0.52) | NOS1AXLKITIDO1METAP2 | |
| SCHEMBL1134888 | 0.82 | CSF1R (0.56) | NOS1AXLKITIDO1METAP2 | |
| Hydrochloric Acid SCHEMBL1056437 | 0.82 | NOS1 (0.50) | NOS1AXLKITIDO1METAP2 | |
| SCHEMBL29360810 | 0.82 | CSF1R (0.56) | NOS1AXLKITIDO1METAP2 | |
| SCHEMBL29702928 | 0.81 | NOS1 (0.53) | NOS1AXLKITIDO1METAP2 | |
| SCHEMBL23481936 | 0.79 | IDO1 (0.51) | NOS1AXLKITIDO1METAP2 | |
| SCHEMBL459667 | 0.78 | METTL3 (0.52) | KITNPC1LMNACYP1A2CYP3A4 | |
| SCHEMBL543898 | 0.78 | METTL3 (0.50) | NOS1AXLKITIDO1NPC1 | |
| SCHEMBL31719176 | 0.78 | METTL3 (0.50) | NOS1AXLKITIDO1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043962-A1 | HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-10-08 | — | — | WO | disclosed |