Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267839 | 0.83 | TAAR1 (0.63) | PRMT6TAAR1CALM1ALDH1A1RAB9A | |
| SCHEMBL9454526 | 0.80 | PRMT6 (0.63) | PRMT6KEAP1TAAR1CETPACMSD | |
| SCHEMBL14141440 | 0.80 | PRMT6 (0.68) | PRMT6KEAP1TAAR1PSMB5ALDH1A1 | |
| SCHEMBL9454365 | 0.80 | PRMT6 (0.63) | PRMT6KEAP1TAAR1CETPPSMB5 | |
| SCHEMBL109478 | 0.80 | TAAR1 (0.70) | PRMT6KEAP1TAAR1PSMB5ALDH1A1 | |
| SCHEMBL12992952 | 0.79 | PRMT6 (1.00) | PRMT6KEAP1TAAR1PSMB5ALDH1A1 | |
| SCHEMBL27761661 | 0.79 | KEAP1 (0.59) | PRMT6KEAP1TAAR1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL1014846 | 0.79 | TAAR1 (0.68) | PRMT6KEAP1TAAR1PSMB5ALDH1A1 | |
| SCHEMBL5664152 | 0.78 | KEAP1 (0.59) | PRMT6KEAP1TAAR1PSMB5ALDH1A1 | |
| SCHEMBL1346211 | 0.77 | PRMT6 (0.59) | PRMT6KEAP1TAAR1CETPACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | claimed |