Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | GAK | O14976 | 1/20 | 0.50 |
| ▸ | STK16 | O75716 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | NEK2 | P51955 | 1/20 | 0.50 |
| ▸ | STK3 | Q13188 | 1/20 | 0.50 |
| ▸ | STK11 | Q15831 | 1/20 | 0.50 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.50 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053845 | 0.79 | AAK1 (0.70) | AAK1PIM1HTTHDAC3HDAC1 | |
| SCHEMBL7110861 | 0.73 | AAK1 (0.72) | AAK1PIM1HTTHDAC3HDAC1 | |
| SCHEMBL1469033 | 0.73 | AAK1 (0.59) | AAK1PIM1HTTHDAC3HDAC1 | |
| SCHEMBL7548968 | 0.73 | AAK1 (0.62) | AAK1PIM1HTTHDAC3HDAC1 | |
| SCHEMBL6643666 | 0.72 | LMNA (0.67) | PIM1HTTHDAC3HDAC1HDAC2 | |
| SCHEMBL1468749 | 0.71 | AAK1 (0.57) | AAK1PIM1HTTHDAC3HDAC1 | |
| SCHEMBL1467820 | 0.71 | AAK1 (0.57) | AAK1PIM1HTTHDAC3HDAC1 | |
| SCHEMBL7112349 | 0.71 | AAK1 (1.00) | AAK1PIM1HDAC3HDAC1HDAC2 | |
| SCHEMBL15643127 | 0.70 | LMNA (0.56) | PIM1HTTHDAC3HDAC1HDAC2 | |
| SCHEMBL7116964 | 0.70 | AAK1 (1.00) | AAK1PIM1HDAC1GAKSTK16 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926810-B | Pyrrolopyridine as kinase inhibitor | 阵列生物制药公司 | 2019-02-19 | — | — | CN | disclosed |