Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 4/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28268990 | 1.00 | NR3C1 (0.33) | NR3C1KDM4EPOLBTACR1ANPEP | |
| SCHEMBL28269000 | 0.90 | TAAR1 (0.39) | KDM4EPOLB | |
| SCHEMBL28268996 | 0.90 | TAAR1 (0.39) | KDM4EPOLB | |
| SCHEMBL28505335 | 0.89 | KDM4E (0.37) | NR3C1KDM4EPOLBNOS3NOS1 | |
| SCHEMBL28505333 | 0.89 | KDM4E (0.37) | NR3C1KDM4EPOLBNOS3NOS1 | |
| SCHEMBL28267269 | 0.88 | DRD2 (0.39) | — | |
| SCHEMBL28267271 | 0.88 | DRD2 (0.39) | — | |
| SCHEMBL28868399 | 0.86 | SIGMAR1 (0.39) | — | |
| SCHEMBL28868398 | 0.86 | SIGMAR1 (0.39) | — | |
| SCHEMBL28508158 | 0.81 | FDFT1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111333-B | Chiral gem-disilyl alkane compound and synthesis method and application thereof | 浙江大学 | 2021-01-08 | — | — | CN | disclosed |
| CN-109111333-A | It is a kind of chiral together with two silicon substrate alkane compounds and its synthetic method and application | 浙江大学 | 2019-01-01 | — | — | CN | disclosed |