Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666265 | 0.86 | CCR1 (0.44) | HTR7HTR1ADRD2HTR2AMAPT | |
| SCHEMBL3922796 | 0.84 | NOS3 (0.45) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL30602371 | 0.84 | KMT2A (0.42) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL12879681 | 0.84 | KMT2A (0.42) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL19602121 | 0.81 | HTR7 (0.38) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL2297589 | 0.80 | HTR7 (0.64) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL2953350 | 0.80 | SQOR (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL28195557 | 0.80 | P2RX7 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13199774 | 0.80 | HTR7 (0.33) | HTR7HTR1ADRD2HTR2AALDH1A1 | |
| SCHEMBL3922793 | 0.78 | CNR2 (0.47) | KDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206580-A | A kind of hybrid cross-linked dynamic aggregation object | 翁秋梅 | 2019-01-15 | — | — | CN | disclosed |