SCHEMBL2827072

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2822035	0.92	SMN1; SMN2 (0.42)	TOP2ALMNAALDH1A1RAB9ATP53
	SCHEMBL15501937	0.89	TOP2A (0.40)	TOP2ALMNAALDH1A1RAB9ATP53
	SCHEMBL2825202	0.87	TP53 (0.38)	TOP2AALDH1A1RAB9ATP53SMN1; SMN2
	SCHEMBL2823787	0.86	ROCK2 (0.45)	TOP2AALDH1A1RAB9ATP53POLB
	SCHEMBL2822824	0.83	SIRT1 (0.40)	TOP2ARAB9ATP53SMN1; SMN2MAPT
	SCHEMBL2825218	0.80	L3MBTL1 (0.41)	TOP2AALDH1A1RAB9ATP53POLB
	SCHEMBL2822912	0.78	TOP2A (0.41)	TOP2ALMNARAB9ATP53SMN1; SMN2
	SCHEMBL2825349	0.76	MAPT (0.40)	TOP2ALMNAALDH1A1RAB9ATP53
	SCHEMBL2830031	0.68	TOP2A (0.46)	TOP2ARAB9ANPC1HDAC1
	SCHEMBL2826834	0.67	TOP2A (0.46)	TOP2AALDH1A1RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.