Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822318 | 0.77 | HSD11B1 (0.38) | — | |
| SCHEMBL2822315 | 0.77 | HSD11B1 (0.38) | — | |
| SCHEMBL2822321 | 0.76 | P2RX7 (0.35) | P2RX7HSD17B10GAALMNAPOLB | |
| SCHEMBL232419 | 0.75 | EPHX2 (0.43) | LMNAPOLBKMT2A | |
| SCHEMBL2827165 | 0.72 | HSD11B1 (0.34) | — | |
| SCHEMBL2824066 | 0.70 | HSD11B1 (0.42) | — | |
| SCHEMBL2828163 | 0.69 | HSD11B1 (0.32) | — | |
| SCHEMBL2824564 | 0.67 | TSHR (0.36) | NPSR1GAALMNA | |
| SCHEMBL2826753 | 0.67 | HSD11B1 (0.41) | LMNA | |
| SCHEMBL232420 | 0.67 | MEN1 (0.36) | P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | claimed |