Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.59 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrochalcone SCHEMBL29359372 | 1.00 | CYP19A1 (0.80) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| Dihydrochalcone SCHEMBL7540273 | 0.98 | CYP19A1 (0.77) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| SCHEMBL1841587 | 0.89 | CYP19A1 (1.00) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| SCHEMBL5793080 | 0.89 | CYP19A1 (0.65) | CYP19A1MAPTALDH1A1HPGDTSHR | |
| SCHEMBL1733117 | 0.86 | CYP19A1 (0.71) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| SCHEMBL30358375 | 0.86 | CYP19A1 (0.71) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| SCHEMBL11880560 | 0.86 | ACHE (0.62) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| SCHEMBL10988386 | 0.86 | CYP19A1 (0.76) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| SCHEMBL3861193 | 0.86 | CYP19A1 (0.61) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| Hydrochloric Acid SCHEMBL3785617 | 0.84 | CYP19A1 (0.69) | CYP19A1MAPTGAASLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120142496-A | Method for detecting impurities in propafenone hydrochloride injection | 华夏生生药业(北京)有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-115124409-A | Preparation method of propafenone hydrochloride intermediate | 山东科源制药股份有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-105431510-B | Organic compounds | 奇华顿股份有限公司 | 2020-02-11 | — | — | CN | claimed |
| EP-2906671-B1 | USE OF 2-HYDROXYPHENYL ARYL KETONES AS FRAGRANCE OR FLAVOR COMPONENTS | GIVAUDAN SA (CH) | 2017-12-06 | — | — | EP | claimed |
| EP-2906671-A2 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2015-08-19 | — | — | EP | claimed |
| US-8877704-B2 | Organic compounds | GIVAUDAN SA (CH) | 2014-11-04 | — | — | US | claimed |
| WO-2014060303-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2014-04-24 | — | — | WO | claimed |
| EP-0123838-B1 | AMINOPROPANOL DERIVATIVES OF 1-(2-HYDROXYPHENYL)-3-PHENYL PROPANOLS, METHOD FOR THEIR MANUFACTURE AND THERAPEUTIC AGENTS CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1986-01-22 | — | — | EP | claimed |
| US-20250243427-A1 | PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS | GIVAUDAN SA (CH) | 2025-07-31 | — | — | US | disclosed |
| CN-120142496-A | Method for detecting impurities in propafenone hydrochloride injection | 华夏生生药业(北京)有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025087998-A1 | ORAL CARE COMPOSITION | GIVAUDAN SA (CH) | 2025-05-01 | — | — | WO | disclosed |
| US-20240417359-A1 | PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS | GIVAUDAN SA (CH) | 2024-12-19 | — | — | US | disclosed |
| EP-4419498-A1 | PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS | Givaudan SA (CH) | 2024-08-28 | — | — | EP | disclosed |
| EP-4419497-A1 | PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS | Givaudan SA (CH) | 2024-08-28 | — | — | EP | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4540697-A | ANTIARRHYTHMIA AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | disclosed |
| US-4460605-A | ANTIARRHYTHMIA AGENTS | HELOPHARM W. PETRIK & CO. (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0075207-A2 | Aminopropanol derivatives of 2-hydroxy-beta-phenyl propiophenones, processes for their preparation and therapeutic agents containing them | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |
| EP-0075207-A2 | Aminopropanol derivatives of 2-hydroxy-beta-phenyl propiophenones, processes for their preparation and therapeutic agents containing them | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |
| WO-1983000688-A1 | 2-AD2'-HYDROXY-3'-(1,1-DIMETHYLPROPYLAMINO)-PROPOXYBD-BETA-PHENYLPROPIOPHENONE, PREPARATION AND PHARMACEUTICAL COMPOSITIONS | HELOPHARM PETRIK CO KG (DE) | 1983-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243427-A1 | PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS | FOS, HAAO, HPD | CYP19A1 240/4885MAPT 1659/4885GAA 1154/4885 |
| US-20240417359-A1 | PRECURSORS OF PHENOLIC FRAGRANT COMPOUNDS | HAAO, FOS, HPD | CYP19A1 185/4885MAPT 1624/4885GAA 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.