SCHEMBL28273633

SCHEMBL28273633

C=CC(=O)C(C(=O)OC)N(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10817225 0.76 ALDH1A1 (0.39) TSHR
SCHEMBL28151201 0.76 LMNA (0.35) TSHR
SCHEMBL18889121 0.74 SMN1; SMN2 (0.36) SMN1; SMN2MEN1KMT2ATSHR
SCHEMBL30540966 0.73 MMP2 (0.43) SMN1; SMN2MEN1KMT2ATSHR
SCHEMBL2552780 0.71 TSHR (0.40) SMN1; SMN2MEN1KMT2ATSHR
SCHEMBL20448168 0.71
SCHEMBL10720609 0.70 SMN1; SMN2 (0.36) SMN1; SMN2MEN1KMT2ATSHR
SCHEMBL20448182 0.69
SCHEMBL9816248 0.69 ALDH1A1 (0.35) TSHR
SCHEMBL27965604 0.68 SMN1; SMN2 (0.34) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109280116-A Constituent, solidfied material, image forming apparatus and image forming method 株式会社理光 2019-01-29 CN disclosed