SCHEMBL28273655

SCHEMBL28273655

Cc1ccccc1S(=O)(=O)C(C)(N)Sc1ccccn1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
SLC40A1 Q9NP59 1/20 0.39
ALDH1A1 P00352 4/20 0.39
EHMT2 Q96KQ7 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
TP53 P04637 1/20 0.37
EDNRA P25101 2/20 0.36
PKM P14618 1/20 0.35
EDNRB P24530 1/20 0.35
ALKBH2 Q6NS38 1/20 0.34
ALKBH3 Q96Q83 1/20 0.34
NPY1R P25929 1/20 0.34
ELANE P08246 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7140571 0.72 EHMT2 (0.40) LMNATDP1SMN1; SMN2HTTKDM4E
SCHEMBL28273653 0.69 ALDH1A1 (0.43) LMNATDP1SMN1; SMN2KDM4EGAA
SCHEMBL28273654 0.69 KMT2A (0.62) LMNATDP1SMN1; SMN2HTTALDH1A1
SCHEMBL2732501 0.69 EHMT2 (0.56) LMNATDP1SMN1; SMN2KDM4EGAA
SCHEMBL13900914 0.66 L3MBTL1 (0.43) LMNATDP1HTTKDM4EGAA
SCHEMBL11027326 0.65 EHMT2 (0.47) LMNATDP1SMN1; SMN2KDM4EALDH1A1
SCHEMBL13811756 0.65 KDM4E (0.50) LMNATDP1SMN1; SMN2HTTKDM4E
SCHEMBL14389434 0.65 HSD11B1 (0.41) TDP1SMN1; SMN2KDM4EGAAALDH1A1
SCHEMBL9965492 0.63 HSD11B1 (0.47) LMNATDP1HTTKDM4EGAA
SCHEMBL28745645 0.63 ALDH1A1 (0.40) LMNATDP1HTTKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109310654-A Particle comprising sulfur-containing compound 诺瓦生命科学有限公司 2019-02-05 CN disclosed