Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140573 | 0.80 | ALDH1A1 (0.49) | EHMT2EHMT1APOBEC3GSMN1; SMN2LMNA | |
| SCHEMBL7133969 | 0.78 | EHMT2 (0.47) | EHMT2EHMT1APOBEC3GSMN1; SMN2LMNA | |
| SCHEMBL28588859 | 0.78 | EHMT2 (0.47) | EHMT2EHMT1APOBEC3GSMN1; SMN2LMNA | |
| SCHEMBL7141184 | 0.78 | ALDH1A1 (0.39) | SMN1; SMN2LMNATDP1GAAHTT | |
| SCHEMBL10848417 | 0.73 | GAA (0.48) | SMN1; SMN2LMNATDP1GAAKDM4E | |
| SCHEMBL28273655 | 0.72 | LMNA (0.40) | EHMT2EHMT1APOBEC3GSMN1; SMN2LMNA | |
| SCHEMBL28273653 | 0.70 | ALDH1A1 (0.43) | SMN1; SMN2LMNATDP1GAAKDM4E | |
| SCHEMBL9803 | 0.69 | KMT2A (0.49) | TDP1GAAKDM4EHTTALDH1A1 | |
| SCHEMBL31515627 | 0.69 | KMT2A (0.49) | TDP1GAAKDM4EHTTALDH1A1 | |
| SCHEMBL7140577 | 0.69 | KMT2A (0.45) | EHMT2EHMT1APOBEC3GSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086124-B1 | NOVEL CYCLOSPORINS | CHEM AG C (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-6583265-B1 | Compound for use in the prevention of viral and bacterial infections | C-CHEM AG (CH) | 2003-06-24 | — | — | US | disclosed |